简述肿瘤浸润和转移的机制。
肿瘤浸润转移的机制较为复杂,目前一般认为,肿瘤细胞的侵袭性生长、迁移等生物学过程的分子机制与肿瘤细胞的上皮之间质转化有密切的关系,而肿瘤细胞的亲器官性转移符合目前较为被大众接受的“种子与土壤学说”,即转移的瘤细胞和利于转移瘤细胞生长的局部组织间的默契。
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